In this study, multiple-source satellite data, high frequency data directly measured by marine meteorological drift buoy, Argo floats data and HYCOM analysis dataset were used to analyze the temporal and spatial variation of Sea Surface Temperature (SST) and vertical sea water temperature profile during the process of super typhoon Lekima（1909）. The results showed that the maximum SST decrease could reach above 5℃ after “Lekima”, the cooling area was more concentrated on the right side of typhoon’s track. “Lekima” resulted in the vertical mixing of near surface water and subsurface water column, and subsurface water column was heated, which increased the depth of the mixed layer and temperature of the deep water. According to the data mentioned above, it was found that the emergence of main SST decreased region was 1-2 days later than the appearance of “Lekima” center area. Among all data, marine drift buoy data could describe the variation in SST more accurately, and could be used as a reference to verificate satellite data, as the drift buoy could directly measure SST in high frequency. Moreover, the cooling effect in different marine region also depended on the marine environment. When “Lekima” was closer to Kuroshio, the cooling effect was concentrated in the mixed layer. On the contrast, when “Lekima” was far from Kuroshio, the cooling effect could extend to the thermocline.